Quinolone-DNA Interaction: Sequence-Dependent Binding to Single-Stranded DNA Reflects the Interaction within the Gyrase-DNA Complex

We have investigated the interaction of quinolones with DNA by a number of methods to establish whether a particular binding mode correlates with quinolone potency. The specificities of the quinolone-mediated DNA cleavage reaction of DNA gyrase were compared for a number of quinolones. Two patterns...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Noble, Christian G., Barnard, Faye M., Maxwell, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149327/
https://ncbi.nlm.nih.gov/pubmed/12604512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.854-862.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados