Efflux-Mediated Resistance to Tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1

Pseudomonas aeruginosa strains are less susceptible to tigecycline (previously GAR-936; MIC, 8 μg/ml) than many other bacteria (P. J. Petersen, N. V. Jacobus, W. J. Weiss, P. E. Sum, and R. T. Testa, Antimicrob. Agents Chemother. 43:738-744, 1999). To elucidate the mechanism of resistance to tigecyc...

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Bibliographic Details
Main Authors: Dean, Charles R., Visalli, Melissa A., Projan, Steven J., Sum, Phaik-Eng, Bradford, Patricia A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149306/
https://ncbi.nlm.nih.gov/pubmed/12604529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.972-978.2003
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