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Mechanism of Fluoroquinolone Resistance Is an Important Factor in Determining the Antimicrobial Effect of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model
Antibacterial effect and emergence of resistance to gemifloxacin and levofloxacin were studied in an in vitro pharmacokinetic model of infection. A panel of Streptococcus pneumoniae strains with known mechanisms of resistance were used; two strains had no known resistance mechanism, two had efflux p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149284/ https://ncbi.nlm.nih.gov/pubmed/12604547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.1096-1100.2003 |
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