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The APC11 RING-H2 Finger Mediates E2-Dependent Ubiquitination

Polyubiquitination marks proteins for degradation by the 26S proteasome and is carried out by a cascade of enzymes that includes ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s). The anaphase-promoting complex or cyclosome (APC/C) comprises a multi...

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Main Authors: Leverson, Joel D., Joazeiro, Claudio A.P., Page, Andrew M., Huang, Han-kuei, Hieter, Philip, Hunter, Tony
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC14921/
https://ncbi.nlm.nih.gov/pubmed/10888670
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