The p41 isoform of invariant chain is a chaperone for cathepsin L

The p41 splice variant of major histocompatibility complex (MHC) class II-associated invariant chain (Ii) contains a 65 aa segment that binds to the active site of cathepsin L (CatL), a lysosomal cysteine protease involved in MHC class II-restricted antigen presentation. This segment is absent from...

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Autors principals: Lennon-Duménil, Ana-Maria, Roberts, Rebecca A., Valentijn, Karine, Driessen, Christoph, Overkleeft, Herman S., Erickson, Ann, Peters, Peter J., Bikoff, Elizabeth, Ploegh, Hidde L., Wolf Bryant, Paula
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149174/
https://ncbi.nlm.nih.gov/pubmed/11483509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4055
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