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The p41 isoform of invariant chain is a chaperone for cathepsin L

The p41 splice variant of major histocompatibility complex (MHC) class II-associated invariant chain (Ii) contains a 65 aa segment that binds to the active site of cathepsin L (CatL), a lysosomal cysteine protease involved in MHC class II-restricted antigen presentation. This segment is absent from...

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Published in:EMBO J
Main Authors: Lennon-Duménil, Ana-Maria, Roberts, Rebecca A., Valentijn, Karine, Driessen, Christoph, Overkleeft, Herman S., Erickson, Ann, Peters, Peter J., Bikoff, Elizabeth, Ploegh, Hidde L., Wolf Bryant, Paula
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4055
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