The ‘sequential allosteric ring’ mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin

Folding to completion of actin and tubulin in the eukaryotic cytosol requires their interaction with cytosolic chaperonin CCT [chaperonin containing tailless complex polypeptide 1 (TCP-1)]. Three-dimensional reconstructions of nucleotide-free CCT complexed to either actin or tubulin show that CCT st...

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Hauptverfasser: Llorca, Oscar, Martín-Benito, Jaime, Grantham, Julie, Ritco-Vonsovici, Monica, Willison, Keith R., Carrascosa, José L., Valpuesta, José M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149171/
https://ncbi.nlm.nih.gov/pubmed/11483510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4065
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