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Propagation of the apoptotic signal by mitochondrial waves

Generation of mitochondrial signals is believed to be important in the commitment to apoptosis, but the mechanisms coordinating the output of individual mitochondria remain elusive. We show that in cardiac myotubes exposed to apoptotic agents, Ca(2+) spikes initiate depolarization of mitochondria in...

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Bibliografiske detaljer
Main Authors: Pacher, Pál, Hajnóczky, György
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149166/
https://ncbi.nlm.nih.gov/pubmed/11483514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4107
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