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Propagation of the apoptotic signal by mitochondrial waves

Generation of mitochondrial signals is believed to be important in the commitment to apoptosis, but the mechanisms coordinating the output of individual mitochondria remain elusive. We show that in cardiac myotubes exposed to apoptotic agents, Ca(2+) spikes initiate depolarization of mitochondria in...

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Detalhes bibliográficos
Main Authors: Pacher, Pál, Hajnóczky, György
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149166/
https://ncbi.nlm.nih.gov/pubmed/11483514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4107
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