Reactivity of Reduced [2Fe-2S] Ferredoxins Parallels Host Susceptibility to Nitroimidazoles

The kinetics of the electron transfer reaction between reduced [2Fe-2S] ferredoxins and select nitroimidazole antimicrobial agents is reported. The ferredoxins from the protozoan Trichomonas vaginalis and the cyanobacterium Anabaena sp. strain 7120 were studied because they are the proximal electron...

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Detalhes bibliográficos
Main Authors: Vidakovic, Momcilo, Crossnoe, Chetlen R., Neidre, Christopher, Kim, Kyonghee, Krause, Kurt L., Germanas, Juris P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149022/
https://ncbi.nlm.nih.gov/pubmed/12499206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.302-308.2003
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