Synergistic Lethal Effect of a Combination of Phage Lytic Enzymes with Different Activities on Penicillin-Sensitive and -Resistant Streptococcus pneumoniae Strains

Pal and Cpl-1, two purified bacteriophage lytic enzymes, were tested for their in vitro activity, alone and in combination, against several serotypes of Streptococcus pneumoniae, including penicillin-resistant strains. The enzymes demonstrated synergism in their ability to cleave the bacterial pepti...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Loeffler, J. M., Fischetti, V. A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.375-377.2003
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