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Synergistic Lethal Effect of a Combination of Phage Lytic Enzymes with Different Activities on Penicillin-Sensitive and -Resistant Streptococcus pneumoniae Strains

Pal and Cpl-1, two purified bacteriophage lytic enzymes, were tested for their in vitro activity, alone and in combination, against several serotypes of Streptococcus pneumoniae, including penicillin-resistant strains. The enzymes demonstrated synergism in their ability to cleave the bacterial pepti...

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Detalhes bibliográficos
Main Authors: Loeffler, J. M., Fischetti, V. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149014/
https://ncbi.nlm.nih.gov/pubmed/12499217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.375-377.2003
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