A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum

It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a fatty acid biosynthetic pathway in the relict plastid of P. falciparum (known as the apicoplast). Thi...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., Cowman, Alan F., Besra, Gurdyal S., McFadden, Geoffrey I.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Susceptibility
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.297-301.2003
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