A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum

It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a fatty acid biosynthetic pathway in the relict plastid of P. falciparum (known as the apicoplast). Thi...

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Autori principali: Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., Cowman, Alan F., Besra, Gurdyal S., McFadden, Geoffrey I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Susceptibility
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC148988/
https://ncbi.nlm.nih.gov/pubmed/12499205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.297-301.2003
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