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Population Pharmacokinetics and Pharmacodynamics of Efavirenz, Nelfinavir, and Indinavir: Adult AIDS Clinical Trial Group Study 398

The present population pharmacokinetic (PK) and pharmacodynamic (PD) study modeled the effects of covariates including drug adherence and the coadministration of protease inhibitors (PIs) on the pharmacokinetics of efavirenz (EFV) and the relationship between EFV exposure and virological failure in...

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Autori principali: Pfister, Marc, Labbé, Line, Hammer, Scott M., Mellors, John, Bennett, Kara K., Rosenkranz, Susan, Sheiner, Lewis B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC148981/
https://ncbi.nlm.nih.gov/pubmed/12499180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.130-137.2003
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