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Population Pharmacokinetics and Pharmacodynamics of Efavirenz, Nelfinavir, and Indinavir: Adult AIDS Clinical Trial Group Study 398

The present population pharmacokinetic (PK) and pharmacodynamic (PD) study modeled the effects of covariates including drug adherence and the coadministration of protease inhibitors (PIs) on the pharmacokinetics of efavirenz (EFV) and the relationship between EFV exposure and virological failure in...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Pfister, Marc, Labbé, Line, Hammer, Scott M., Mellors, John, Bennett, Kara K., Rosenkranz, Susan, Sheiner, Lewis B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.130-137.2003
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