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Naturally Occurring Extended-Spectrum Cephalosporinases in Escherichia coli

Genetic and functional characterization of the cephalosporinases produced by 65 clonally unrelated clinical Escherichia coli isolates revealed genetic diversity of the ampC genes and showed that Gln287, Cys287, Pro296, Leu298, and Phe350 substitutions were involved in extension of the hydrolysis spe...

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Bibliographic Details
Main Authors: Mammeri, Hedi, Poirel, Laurent, Fortineau, Nicolas, Nordmann, Patrice
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489779/
https://ncbi.nlm.nih.gov/pubmed/16801449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01633-05
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