AmpC β-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins

Cloning, sequencing, and biochemical analysis identified a novel AmpC-type β-lactamase conferring resistance to extended-spectrum cephalosporins in an Escherichia coli clinical isolate. This enzyme, exhibiting 14 amino acid substitutions compared to a reference AmpC cephalosporinase of E. coli, hydr...

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Main Authors: Mammeri, Hedi, Nazic, Hasan, Naas, Thierry, Poirel, Laurent, Léotard, Sophie, Nordmann, Patrice
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC521871/
https://ncbi.nlm.nih.gov/pubmed/15388478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4050-4053.2004
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