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Evaluation of Protection Afforded by Brucella abortus and Brucella melitensis Unmarked Deletion Mutants Exhibiting Different Rates of Clearance in BALB/c Mice

Research for novel Brucella vaccines has focused upon the development of live vaccine strains, which have proven more efficacious than killed or subunit vaccines. In an effort to develop improved vaccines, signature-tagged mutant banks were screened to identify mutants attenuated for survival. Mutan...

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Autors principals: Kahl-McDonagh, M. M., Ficht, T. A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489724/
https://ncbi.nlm.nih.gov/pubmed/16790778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01787-05
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