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Comparison of Different Live Vaccine Strategies In Vivo for Delivery of Protein Antigen or Antigen-Encoding DNA and mRNA by Virulence-Attenuated Listeria monocytogenes

Listeria monocytogenes can be used to deliver protein antigens or DNA and mRNA encoding such antigens directly into the cytosol of host cells because of its intracellular lifestyle. In this study, we compare the in vivo efficiencies of activation of antigen-specific CD8 and CD4 T cells when the anti...

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Auteurs principaux: Loeffler, Daniela I. M., Schoen, Christoph U., Goebel, Werner, Pilgrim, Sabine
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489688/
https://ncbi.nlm.nih.gov/pubmed/16790768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00112-06
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