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Growth, Virulence, and Immunogenicity of Listeria monocytogenes aro Mutants

Mutants of Listeria monocytogenes with deletions in genes of the common branch of the biosynthesis pathway leading to aromatic compounds were constructed as possible virulence-attenuated carrier strains for protein antigens or vaccine DNA. aroA, aroB, and in particular aroE mutants showed strongly r...

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Bibliografiske detaljer
Main Authors: Stritzker, Jochen, Janda, Jozef, Schoen, Christoph, Taupp, Marcus, Pilgrim, Sabine, Gentschev, Ivaylo, Schreier, Peter, Geginat, Gernot, Goebel, Werner
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC517589/
https://ncbi.nlm.nih.gov/pubmed/15385459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5622-5629.2004
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