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Growth, Virulence, and Immunogenicity of Listeria monocytogenes aro Mutants

Mutants of Listeria monocytogenes with deletions in genes of the common branch of the biosynthesis pathway leading to aromatic compounds were constructed as possible virulence-attenuated carrier strains for protein antigens or vaccine DNA. aroA, aroB, and in particular aroE mutants showed strongly r...

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Detalhes bibliográficos
Main Authors: Stritzker, Jochen, Janda, Jozef, Schoen, Christoph, Taupp, Marcus, Pilgrim, Sabine, Gentschev, Ivaylo, Schreier, Peter, Geginat, Gernot, Goebel, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517589/
https://ncbi.nlm.nih.gov/pubmed/15385459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5622-5629.2004
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