gyrA Mutations in Ciprofloxacin-Resistant Bartonella bacilliformis Strains Obtained In Vitro

We isolated and characterized mutants of Bartonella bacilliformis that are resistant to the fluoroquinolone antibiotic ciprofloxacin, which targets the A subunit of DNA gyrase. Mutants had single point mutations in the gyrA gene that changed either Asp-90 to Gly or Asp-95 to Asn and had 3- or 16-fol...

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Detaylı Bibliyografya
Asıl Yazarlar: Minnick, Michael F., Wilson, Zachary R., Smitherman, Laura S., Samuels, D. Scott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC148966/
https://ncbi.nlm.nih.gov/pubmed/12499219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.383-386.2003
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