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Ca(2+)-Dependent Maturation of Subtilisin from a Hyperthermophilic Archaeon, Thermococcus kodakaraensis: the Propeptide Is a Potent Inhibitor of the Mature Domain but Is Not Required for Its Folding

Subtilisin from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 is a member of the subtilisin family. T. kodakaraensis subtilisin in a proform (T. kodakaraensis pro-subtilisin), as well as its propeptide (T. kodakaraensis propeptide) and mature domain (T. kodakaraensis mat-subtilisin)...

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Bibliografiske detaljer
Main Authors: Pulido, Marian, Saito, Kenji, Tanaka, Shun-Ichi, Koga, Yuichi, Morikawa, Masaaki, Takano, Kazufumi, Kanaya, Shigenori
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489632/
https://ncbi.nlm.nih.gov/pubmed/16751527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02696-05
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