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Lamivudine Resistance of Hepatitis B Virus Masked by Coemergence of Mutations in Probe Region of the COBAS AMPLICOR Assay

The COBAS AMPLICOR hepatitis B virus assay targets a conserved region of the genome and is widely used to monitor treatment of hepatitis B in order to identify emerging resistance. However, the assay failed to recognize increasing viremia levels when YMDD mutations were paralleled by mutations in th...

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Bibliographic Details
Main Authors: Lindh, Magnus, Hannoun, Charles, Malmström, Sebastian, Lindberg, Johan, Norkrans, Gunnar
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489515/
https://ncbi.nlm.nih.gov/pubmed/16825388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00265-06
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