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Mechanisms downstream of reverse transcription reduce serum levels of HBV DNA but not of HBsAg in chronic hepatitis B virus infection

BACKGROUND: Hepatitis B virus (HBV) DNA in serum of chronically infected patients declines by 3–4 log(10) units at loss of HBe antigen (HBeAg) from serum. The mechanisms behind this decline, and the much smaller decline of surface antigen (HBsAg) levels, are still not well known. The aim of this stu...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Larsson, Simon B., Malmström, Sebastian, Hannoun, Charles, Norkrans, Gunnar, Lindh, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673857/
https://ncbi.nlm.nih.gov/pubmed/26645241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0447-5
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