Rapid Detection of Rifampin Resistance in Mycobacterium tuberculosis by Pyrosequencing Technology

We developed an assay for rapid detection of rifampin resistance in Mycobacterium tuberculosis based on Pyrosequencing technology, involving a technique for real-time sequencing. A 180-bp region of the rpoB gene was amplified in clinical isolates of both rifampin-resistant and -susceptible M. tuberc...

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Bibliographic Details
Main Authors: Jureen, Pontus, Engstrand, Lars, Eriksson, Solveig, Alderborn, Anders, Krabbe, Margareta, Hoffner, Sven E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489404/
https://ncbi.nlm.nih.gov/pubmed/16757581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02210-05
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