The Cell Lysis Activity of the Streptococcus agalactiae Bacteriophage B30 Endolysin Relies on the Cysteine, Histidine-Dependent Amidohydrolase/Peptidase Domain

The Streptococcus agalactiae bacteriophage B30 endolysin contains three domains: cysteine, histidine-dependent amidohydrolase/peptidase (CHAP), Acm glycosidase, and the SH3b cell wall binding domain. Truncations and point mutations indicated that the Acm domain requires the SH3b domain for activity,...

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Detalhes bibliográficos
Main Authors: Donovan, David M., Foster-Frey, Juli, Dong, Shengli, Rousseau, Geneviève M., Moineau, Sylvain, Pritchard, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489305/
https://ncbi.nlm.nih.gov/pubmed/16820517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03065-05
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