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Investigation of the Mechanism of Meiotic DNA Cleavage by VMA1-Derived Endonuclease Uncovers a Meiotic Alteration in Chromatin Structure around the Target Site

VMA1-derived endonuclease (VDE), a homing endonuclease in Saccharomyces cerevisiae, is encoded by the mobile intein-coding sequence within the nuclear VMA1 gene. VDE recognizes and cleaves DNA at the 31-bp VDE recognition sequence (VRS) in the VMA1 gene lacking the intein-coding sequence during meio...

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Detalhes bibliográficos
Main Authors: Fukuda, Tomoyuki, Ohta, Kunihiro, Ohya, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489271/
https://ncbi.nlm.nih.gov/pubmed/16757746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00052-06
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