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The Redox State of SECIS Binding Protein 2 Controls Its Localization and Selenocysteine Incorporation Function

Selenoproteins are central controllers of cellular redox homeostasis. Incorporation of selenocysteine (Sec) into selenoproteins employs a unique mechanism to decode the UGA stop codon. The process requires the Sec insertion sequence (SECIS) element, tRNA(Sec), and protein factors including the SECIS...

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Autors principals: Papp, Laura V., Lu, Jun, Striebel, Frank, Kennedy, Derek, Holmgren, Arne, Khanna, Kum Kum
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489162/
https://ncbi.nlm.nih.gov/pubmed/16782878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02284-05
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