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Reconstitution of selenocysteine incorporation reveals intrinsic regulation by SECIS elements

Selenoproteins are present in all three domains of life and are responsible for a major part of a cell’s antioxidant defense against reactive oxygen species. Synthesis of selenoproteins requires the decoding of a UGA codon as selenocysteine (Sec) instead of translation termination. Sec is incorporat...

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Détails bibliographiques
Auteurs principaux: Gupta, Nirupama, DeMong, Louise W., Banda, Sowmya, Copeland, Paul R.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699960/
https://ncbi.nlm.nih.gov/pubmed/23624110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.016
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