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Congenital Hypothyroidism (Cretinism) in neuroD2-Deficient Mice
Mice lacking neuroD2, a basic helix-loop-helix transcription factor involved in brain development, show growth retardation and other abnormalities consistent with hypothalamic-pituitary-thyroid (HPT) axis dysfunction. neuroD2 is expressed in the paraventricular hypothalamic nuclei, the anterior lobe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489089/ https://ncbi.nlm.nih.gov/pubmed/16705180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02158-05 |
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