Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type restricted basic helix–loop–helix (bHLH) gene, BETA2/NeuroD, expressed in pancreatic endocrine cells, the intestine, and the brain, activates ins...

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Bibliografiska uppgifter
Huvudupphovsmän: Naya, Francisco J., Huang, Hsiang-Po, Qiu, Yuhong, Mutoh, Hiroyuki, DeMayo, Francesco J., Leiter, Andrew B., Tsai, Ming-Jer
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 1997
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC316513/
https://ncbi.nlm.nih.gov/pubmed/9308961
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