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Optimal Long-Term Humoral Responses to Replication-Defective Herpes Simplex Virus Require CD21/CD35 Complement Receptor Expression on Stromal Cells

Replication-defective herpes simplex virus (HSV) strains elicit durable immune responses and protect against virulent HSV challenge in mice, despite being unable to establish latent infection in neuronal cells. Mechanisms for generating long-lived immunity in the absence of viral persistence remain...

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Main Authors: Brockman, Mark A., Verschoor, Admar, Zhu, Jia, Carroll, Michael C., Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489035/
https://ncbi.nlm.nih.gov/pubmed/16809316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01421-05
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