Conformational States of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Ectodomain

The severe acute respiratory syndrome coronavirus enters cells through the activities of a spike protein (S) which has receptor-binding (S1) and membrane fusion (S2) regions. We have characterized four sequential states of a purified recombinant S ectodomain (S-e) comprising S1 and the ectodomain of...

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Bibliographic Details
Main Authors: Li, Fang, Berardi, Marcelo, Li, Wenhui, Farzan, Michael, Dormitzer, Philip R., Harrison, Stephen C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489032/
https://ncbi.nlm.nih.gov/pubmed/16809285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02744-05
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