Involvement of Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutations in the Regulation of Resistance to Nucleoside Inhibitors

We characterized 16 additional mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) whose role in drug resistance is still unknown by analyzing 1,906 plasma-derived HIV-1 subtype B pol sequences from 551 drug-naïve patients and 1,355 nucleoside RT inhibitor (NRTI)-trea...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Svicher, Valentina, Sing, Tobias, Santoro, Maria Mercedes, Forbici, Federica, Rodríguez-Barrios, Fátima, Bertoli, Ada, Beerenwinkel, Niko, Bellocchi, Maria Concetta, Gago, Federigo, d'Arminio Monforte, Antonella, Antinori, Andrea, Lengauer, Thomas, Ceccherini-Silberstein, Francesca, Perno, Carlo Federico
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2006
विषय:
Vaccines and Antiviral Agents
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489024/
https://ncbi.nlm.nih.gov/pubmed/16809324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02084-05
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