Nrf Transcription Factors in Keratinocytes Are Essential for Skin Tumor Prevention but Not for Wound Healing

The Nrf2 transcription factor is a key player in the cellular stress response through its regulation of cytoprotective genes. In this study we determined the role of Nrf2-mediated gene expression in keratinocytes for skin development, wound repair, and skin carcinogenesis. To overcome compensation b...

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Huvudupphovsmän: auf dem Keller, Ulrich, Huber, Marcel, Beyer, Tobias A., Kümin, Angelika, Siemes, Christina, Braun, Susanne, Bugnon, Philippe, Mitropoulos, Varvara, Johnson, Delinda A., Johnson, Jeffrey A., Hohl, Daniel, Werner, Sabine
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489009/
https://ncbi.nlm.nih.gov/pubmed/16648473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3773-3784.2006
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