Non-Macrophage-Tropic Human Immunodeficiency Virus Type 1 R5 Envelopes Predominate in Blood, Lymph Nodes, and Semen: Implications for Transmission and Pathogenesis

Human immunodeficiency virus type 1 (HIV-1) R5 isolates that predominantly use CCR5 as a coreceptor are frequently described as macrophage tropic. Here, we compare macrophage tropism conferred by HIV-1 R5 envelopes that were derived directly by PCR from patient tissue. This approach avoids potential...

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Detalhes bibliográficos
Main Authors: Peters, Paul J., Sullivan, W. Matthew, Duenas-Decamp, Maria J., Bhattacharya, Jayanta, Ankghuambom, Chiambah, Brown, Richard, Luzuriaga, Katherine, Bell, Jeanne, Simmonds, Peter, Ball, Jonathan, Clapham, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488974/
https://ncbi.nlm.nih.gov/pubmed/16775320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02328-05
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