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A Highly Restricted T-Cell Receptor Dominates the CD8(+) T-Cell Response to Parvovirus B19 Infection in HLA-A*2402-Positive Individuals
Six of seven HLA-A*2402-positive individuals with acute parvovirus B19 infections made vigorous CD8-positive cytotoxic T-cell (CTL) responses to the viral epitope FYTPLADQF. All responders showed highly focused T-cell receptor (TCR) usage, using almost exclusively BV5.1. The BV5.1 TCR dominated the...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1488968/ https://ncbi.nlm.nih.gov/pubmed/16775358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02388-05 |
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