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The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols

Mice with a targeted mutation of 3β-hydroxysterol Δ(7)-reductase (Dhcr7) that cannot convert 7-dehydrocholesterol to cholesterol were used to identify the origin of fetal sterols. Because their heterozygous mothers synthesize cholesterol normally, virtually all sterols found in a Dhcr7 knockout fetu...

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Detalhes bibliográficos
Main Authors: Tint, G. S., Yu, Hongwei, Shang, Quan, Xu, Guorong, Patel, Shailendra B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488821/
https://ncbi.nlm.nih.gov/pubmed/16651660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M600141-JLR200
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