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The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols
Mice with a targeted mutation of 3β-hydroxysterol Δ(7)-reductase (Dhcr7) that cannot convert 7-dehydrocholesterol to cholesterol were used to identify the origin of fetal sterols. Because their heterozygous mothers synthesize cholesterol normally, virtually all sterols found in a Dhcr7 knockout fetu...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1488821/ https://ncbi.nlm.nih.gov/pubmed/16651660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M600141-JLR200 |
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