Protection against Fatal Pseudomonas aeruginosa Pneumonia in Mice after Nasal Immunization with a Live, Attenuated aroA Deletion Mutant

Studies of immunity to Pseudomonas aeruginosa have indicated that a variety of potential immunogens can elicit protection in animal models, utilizing both antibody- and cell-mediated immune effectors for protection. To attempt to optimize delivery of multiple protective antigens and elicit a broad r...

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Autores principales: Priebe, Gregory P., Meluleni, Gloria J., Coleman, Fadie T., Goldberg, Joanna B., Pier, Gerald B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC148856/
https://ncbi.nlm.nih.gov/pubmed/12595463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1453-1461.2003
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