Rho GTPase Is Activated by Cytotoxic Necrotizing Factor 1 in Peripheral Blood T Lymphocytes: Potential Cytotoxicity for Intestinal Epithelial Cells

Some strains of Escherichia coli related to acute cystitis or colitis produce a toxin named cytotoxic necrotizing factor 1 (CNF-1). CNF-1 mediates its effects on epithelial cells or phagocytes via the permanent activation of small GTP-binding proteins, caused by the toxin-induced deamidation of Glu(...

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Pubblicato in:	Infect Immun
Autori principali:	Brest, Patrick, Mograbi, Baharia, Hofman, Véronique, Loubat, Agnès, Rossi, Bernard, Auberger, Patrick, Hofman, Paul
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Molecular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.3.1161-1169.2003
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