Mutagenic properties of the 8-amino-2'-deoxyguanosine DNA adduct in mammalian cells.

The DNA adduct 8-amino-2'-deoxyguanosine (8-amino-dG) is found in liver DNA of rats treated with the hepatocarcinogen 2-nitropropane. Site-specifically modified oligodeoxynucleotides were used to explore the mutagenic potential of 8-amino-dG in simian kidney (COS-7) cells. Oligodeoxynucleotides (5'-...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Tan, X, Suzuki, N, Johnson, F, Grollman, A P, Shibutani, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10325419/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.11.2310
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