An NMR and molecular modelling analysis of d(CTACTGCTTTAG). d(CTAAAGCAGTAG) reveals that the particular behaviour of TpA steps is related to edge-to-edge contacts of their base-pairs in the major groove.

In a previous NMR study we detected the presence of particular motions and hydration properties within the DNA fragment d(CTACTGCTTTAG).d(CTAAAGCAGTAG). Now, we report on an NMR and molecular modelling analysis of this sequence focusing our attention on the biologically important TpA steps. NOe and...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Leporc, S, Mauffret, O, Tevanian, G, Lescot, E, Monnot, M, Fermandjian, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1999
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148776/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.4759
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