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Nuclear targeting determinants of the phage P1 cre DNA recombinase.

The Cre DNA recombinase of bacteriophage P1 has become a useful tool for genomic manipulation in mice and other eukaryotes. Because Cre is of prokaryotic origin, the 38 kDa protein has been presumed to gain access to the eukaryotic nucleus simply because it is sufficiently small to pass through the...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Le, Y, Gagneten, S, Tombaccini, D, Bethke, B, Sauer, B
Format: Artigo
Language:Inglês
Published: Oxford University Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.4703
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