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Truncation Mutants of the Tight Junction Protein ZO-1 Disrupt Corneal Epithelial Cell Morphology

The tight junction is the most apical intercellular junction of epithelial cells and regulates transepithelial permeability through the paracellular pathway. To examine possible functions for the tight junction-associated protein ZO-1, C-terminally truncated mutants and a deletion mutant of ZO-1 wer...

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Autors principals: Ryeom, Sandra W., Paul, David, Goodenough, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC14876/
https://ncbi.nlm.nih.gov/pubmed/10793144
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