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Endoplasmic Reticulum Quality Control of Oligomeric Membrane Proteins: Topogenic Determinants Involved in the Degradation of the Unassembled Na,K-ATPase α Subunit and in Its Stabilization by β Subunit Assembly

The molecular nature of determinants that mediate degradation of unassembled, polytopic subunits of oligomeric membrane proteins and their stabilization after partner subunit assembly is largely unknown. Expressing truncated Na,K-ATPase α subunits alone or together with β subunits, we find that in u...

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Main Authors: Béguin, Pascal, Hasler, Udo, Staub, Olivier, Geering, Käthi
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2000
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14874/
https://ncbi.nlm.nih.gov/pubmed/10793142
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