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Emergence of Protein Fold Families through Rational Design

Diverse proteins with similar structures are grouped into families of homologs and analogs, if their sequence similarity is higher or lower, respectively, than 20%–30%. It was suggested that protein homologs and analogs originate from a common ancestor and diverge in their distinct evolutionary time...

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Bibliografiske detaljer
Main Authors: Ding, Feng, Dokholyan, Nikolay V
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1487181/
https://ncbi.nlm.nih.gov/pubmed/16839198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020085
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