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Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as well as on crossover position. Using both public database analysis and wet-bench approaches, we revisite...

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Detalhes bibliográficos
Main Authors: Sandovici, Ionel, Kassovska-Bratinova, Sacha, Vaughan, Joe E, Stewart, Rae, Leppert, Mark, Sapienza, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1487178/
https://ncbi.nlm.nih.gov/pubmed/16839189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020101
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