Loading...

Gene targeted DNA double-strand break induction by (125)I-labeled triplex-forming oligonucleotides is highly mutagenic following repair in human cells.

A parallel binding motif 16mer triplex-forming oligonucleotide (TFO) complementary to a polypurine-polypyrimidine target region near the 3'-end of the SupF gene of plasmid pSP189 was labeled with [5-(125)I]dCMP at position 15. Following triplex formation and decay accumulation, radiation-induce...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mezhevaya, K, Winters, T A, Neumann, R D
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148705/
https://ncbi.nlm.nih.gov/pubmed/10518622
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!