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Mitotic Regulation of the APC Activator Proteins CDC20 and CDH1

The ordered activation of the ubiquitin protein ligase anaphase-promoting complex (APC) or cyclosome by CDC20 in metaphase and by CDH1 in telophase is essential for anaphase and for exit from mitosis, respectively. Here, we show that CDC20 can only bind to and activate the mitotically phosphorylated...

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Bibliografiske detaljer
Main Authors: Kramer, Edgar R., Scheuringer, Nadja, Podtelejnikov, Alexandre V., Mann, Matthias, Peters, Jan-Michael
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14867/
https://ncbi.nlm.nih.gov/pubmed/10793135
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